I traveled with my husband on business three days a week (two nights), for 7 months, with my dog. We always stayed at LaQuinta because it was pet-friendly, with no extra charge for Mac (80 lb. Lab). They said I could bring a dog of any size that was a non-aggressive breed. When we went on vacation, and were going to stay at a different LaQuinta, their site said no dogs over 50 lbs, but when I called and told them that I regularly stayed with Mac at another of their hotels, they said I could bring him. Don't be afraid to ask.
I feed raw, so I always got a room with a fridge. At first, I would take food with me, but it really was easier to pay more and buy food at a grocery store when I got there and feed it in the parking lot on the styrofoam tray it came in. Also, he did not feel comfortable enough when traveling to eat "big food", like leg quarters so he got a lot of ground meat, trim and chicken feet.
The most helpful thing I did was teach Mac a "Go to your place command", and then I took his place (bed) with me every time. It helped him know what to do right away. The other useful thing I taught him was "Wait" before he got out of the car-so there would be no botling into parking lots and the like.
I second the advice to leave the room as undoggy as possible. I also tried to make sure Mac was on his best behavior in the elevator/lobby. You may find that your dogs are frightened by the elevator, or even the stairwell. Mac was not at all fearful normally, but these things scared him a lot.
If you are traveling far away, bring water-sometimes new water makes dogs sick (It did Mac). I just bought gallons from Wal-mart.
If you should happen to leave them, having some kind of noise (like the tv on low) will help to muffle outside noises that may upset them. If you do step out-even just to the ice machine, leave a Do Not Disturb sign on your door, so a maid does not get the surprise of her life entering your room! :lol:
Enjoy your trip! Have fun with your dogs!
Marie